Research Library

Peptide research, regulatory updates, and protocol intelligence.

Grounded in peer-reviewed literature and FDA prescribing data — the same sources that power the PeptidesGPT AI Coach.

June 22, 2026·7 min read

Bloomberg Just Put Peptides on the Cover. Here's What It Got Right — And What the Story Missed.

Bloomberg Businessweek's peptide cover story describes a multibillion-dollar gold rush. Here's the context the article didn't have space to explain — and what it means for anyone navigating this space.

BPC-157TB-500MOTS-csemaglutide
June 18, 2026·6 min read

Why I Stopped Chasing My Goal Weight — And What I Track Instead

I hit my goal weight of 168 lbs — and my body composition data told a different story: muscle down, body fat up. Here's why I track SMM and body-fat %, not just the scale.

SemaglutideTirzepatide
June 9, 2026·7 min read

What Lilly's Top Obesity Executive Just Said About the Future of Metabolic Medicine

At the Goldman Sachs 47th Annual Healthcare Conference, Lilly's EVP of Cardiometabolic Health framed GIP, GLP-1, and amylin as the three hormones that belong together. Here's what that signals.

tirzepatideeloralintideretatrutide
June 3, 2026·6 min read

You're on a GLP-1. Here's Why You Need a System Before You Stop

The compounded GLP-1 market closes June 29, 2026. STEP 1 trial data shows ~2/3 of lost weight returns after stopping. Here's how to build a tracking system before access changes.

semaglutidetirzepatide
June 1, 2026·5 min read

BPC-157's First Randomized Human Clinical Trial: What NCT07437547 Actually Tells Us

A Phase 2 randomized controlled trial of BPC-157 for hamstring muscle strain has been registered on ClinicalTrials.gov. Here's what that means — and what it doesn't.

BPC-157
May 30, 2026·5 min read

The GLP-1 Rebound Problem: What the Clinical Data Actually Shows — and What to Do About It

Two-thirds of weight lost on semaglutide returns within 12 months of stopping. The STEP 1 and SURMOUNT-4 trial data explains why — and what the research says actually helps.

SemaglutideTirzepatide
May 28, 2026·6 min read

TRIUMPH-1: Why the Most Interesting Number in Retatrutide's Phase 3 Trial Isn't 28%

Eli Lilly's TRIUMPH-1 Phase 3 trial showed 28% weight loss at 12mg retatrutide. But the real story is in the 4mg column — and it changes how most patients should think about this drug.

RetatrutideSemaglutideTirzepatideOrforglipron
May 26, 2026·7 min read

Women, GLP-1s, and Lean Mass: What the Research Actually Shows About Muscle Preservation During Fat Loss

GLP-1 medications cause both fat and muscle loss in women. Here's what the research says about preserving lean mass during fat loss — and why it matters more than the number on the scale.

SemaglutideTirzepatide
May 24, 2026·9 min read

How Long Can You Stay On Peptides? The Three-Bucket Framework

Most peptide cycle length advice is wrong because it ignores mechanism. Here's the three-bucket framework that tells you when to run forever, when to stop, and when to cycle hard.

BPC-157GHK-CuCJC-1295Ipamorelin
May 12, 2026·5 min read

BPC-157, TB-500, and Epithalon: What's Actually Happening with FDA Reclassification in 2026

BPC-157 and TB-500 left the FDA's Category 2 restricted list on April 23, 2026. The FDA's PCAC meets July 23–24 to formally review 7 peptides for 503A approval. Here's what actually happened.

BPC-157TB-500EpithalonSemax
May 12, 2026·7 min read

Forzinity (SS-31) Receives FDA Accelerated Approval — Here's What It Means for the Peptide Field

SS-31 (Forzinity) received FDA accelerated approval in September 2025 for mitochondrial dysfunction — the first peptide of its class to cross from gray market to approved drug.

SS-31ElamipretideMOTS-cEpithalon